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Notably, exendin 939 alleviated CAP-induced acute pain, as well as chronic pain induced by complete Freunds adjuvant (CFA) and spared nerve injury (SNI), in mice without causing hyperthermia associated with other TRPV1 inhibitors

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5 showed that hippocampal neurogenesis is required for the behavioral effects of current antidepressants in the novelty-suppressed feeding paradigm in mice, but that reduced neurogenesis per se does not alter the mice latency to feed at the novelty-suppressed feeding