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Mechanism of action Retatrutide activates the GIP, GLP-1, and GCG receptors simultaneously, which may lead to better weight loss and cardiometabolic benefits compared to targeting a single receptor

The drugs, including semaglutide (Ozempic, Wegovy and Rybelsus), tirzepatide (Mounjaro and Zepbound) and retatrutide (still in clinical trials), are used to treat both diabetes and obesity

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Para Zepbound (manejo de peso), la titulacin incluye pasos adicionales (2.5, 5, 7.5, 10, 12.5 y 15 mg), lo que significa que la dosis de mantenimiento ptima puede no alcanzarse hasta varios meses despus del inicio del tratamiento