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May 28, 2015
Discrete brain areas express the insulin-responsive glucose transporter GLUT4
Adding to the statement, adding electron donating groups (n-butyl, methoxy, etc.) at the benzene ring was found to decrease the potency of DPP-4 inhibitors, whereas substituting electron donating group (EDG) with electron withdrawing groups (EWG) like: bromo, and nitro) tended to enhance the activity, comparing the potency of the compounds within halogen substituting (Bromo to chloro or CF 3 ) displays to see a reduction in inhibitory potency [58] (Figure 10 C,D)
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Patients were categorized as no AF, kAF, or AFDAS
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