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The first-in-human phase I trial APEX-01 is investigating ARX517, a PSMA-targeting antibody conjugated to the auristatin amberstatin 269 (AS269) that inhibits microtubule polymerization

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Roche in its statement said these Phase II results will help build the case for advancing CT-388 into late-stage testing, which is set to get underway this quarter

So the financial impact may not be as steep as it would appear

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