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Until recently, clinical studies of MRA in CKD had not looked at hard outcomes, although there is increased risk of hyperkalemia as demonstrated by a Cochrane review summarizing the literature up to but excluding Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (FIDELIO-DKD) [98]
However, the medication may cause stomach side effects that may feel like early signs of diverticulitis
Separately, a spokesperson for FDA's Center for Drug Evaluation and Research , said it was possible compounded semaglutide is exempt from normal FDA approval if it is "made using a bulk drug substance (active ingredient) that is a component of an FDA-approved human drug product, provided all other conditions
There was no difference between T2 and T1
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