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I think its important to note, however, that this does not invalidate the initial weight loss or the potential popularity of these drugs - nor the chances that patients may stay on them indefinitely

Neuro Endocrinol Lett 2010

In contrast, the lower expression of GLP-1R on -cells results in a limited direct effect

Most GLP-1s can be kept at room temperature, below 86F (30C), for a short period, between 14 to 56 days , depending on the specific medication, before they must be discarded Related article: Is Your Semaglutide Safe

Key Takeaways Average weight loss for semaglutide and other GLP-1s How much weight should you lose on Mounjaro