They are losing weight visibly and feeling more capable, which (per Morgan Stanleys February 2024 survey of ~300 GLP-1 users) tracks with weekly workout rates jumping from 35% to 77% after starting the drug
Tardif JC, Kouz S, Waters David D, Bertrand OF et al (2019) Efficacy and safety of low-dose colchicine after myocardial infarction
And in the sevens we might be missing that somebody actually has rolling hills, but theyre up at a higher number
What Users Actually Experience (Not Just Theory) Instead of clinical terms, heres how most people describe GLP-1 side effects: I feel full even after a few bites I get slightly nauseous after eating My digestion feels slow or heavy I dont feel hungry, but I also feel low energy These effects are directly linked to how GLP-1 drugs influence appetite and digestion
However, the FDA label explicitly states that "it is unknown whether GLP-1 receptor agonists cause thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of GLP-1 receptor agonist-induced rodent thyroid C-cell tumors has not been determined." The rodent thyroid has substantially more C-cells than the human thyroid, and rodents may be more susceptible to this effect
