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When to talk to your provider Reach out sooner rather than later if youve reached your maintenance dose and notice little to no change in appetite, if side effects are severe enough to interfere with daily life, or if hunger suddenly returns after being well controlled

Researchers suspect this reflects hormonal optimization in men with functional hypogonadism related to excess weight, which may translate into improved sexual desire, erectile function, and spermatogenesis

The combination of these effects results in more robust insulin secretion and improved insulin sensitivity

"You'll be monitored on each dose as you increase, to find the one that can control your blood sugar effectively," Sowa says

Front Genet 13:1022739