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However, unlike GLP-1R agonists, DPP-4 inhibitors do not cause significant reductions in body weight (Meneghini et al., 2011

As a result of these unprecedented dynamics and high demand for semaglutide products, we believe it is our responsibility to continue to raise awareness, to reinforce responsible use of our medicines and, ultimately, to support patient safety and positive clinical outcomes. When health care providers prescribe medications for unapproved uses, its known as an off-label use. Some off-label uses of medication can have benefits for patients, but there are also potential risks

Because of the potential for adverse effects on a nursing baby, use during breastfeeding is usually not recommended unless the expected benefit to the mother clearly outweighs any possible risk to the child

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