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Therefore, it remains unclear whether the reduction of steatosis observed in animal and human trials in response to treatment with GLP-1R agonists results from direct activation of hepatic GLP-1R or the indirect impact such as weight loss, increased insulin sensitivity, brain-liver signals such as brain leptin 51 , or other hormonal signals that these agonists might trigger 14

Regular monitoring of weight and wellbeing, ideally with professional support, helps ensure the approach remains safe and effective over time

In Table 2 the mechanism of action and indications of diuretics are shown

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Others may benefit if you're struggling to consume enough sodium, and some may simply help you sip more consistently throughout the day