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A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis

In contrast, studies on human senior subjects show that low IGF-1 levels are associated with poor knee extensor muscle strength, slow walking speed, and difficulty with mobility tasks [6]

10.1038/nrg816 37 JoveR

People with this chronic, progressive neurological disorder have high levels of oxidative stress and premature cellular die off in a part of the brain called the substantia nigra

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