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These results were consistent with earlier murine data [53] where calorie restriction was noted to extend lifespan by increasing cellular NAD+/NADH ratio, promoting expression of peroxisome proliferator-activated receptors, and activating SIRT1 [53]

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The lot number is an authentic lot number, and only when both the lot number is coupled with the eight digits, the FDA says it is counterfeit and should not be used