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Description

PET imaging allows for a direct measurement of synapses in the living human brain using the radioligand [ 11 C]UCB-J, that binds to the synaptic vesicle protein 2A (SV2A), a protein that is expressed ubiquitously on synaptic vesicles throughout the brain and acts as a marker of synaptic density [240]

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For 80%-90% of people with systemic mastocytosis, a mutation in the KIT gene is the cause

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