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Bariatric surgery may reduce knee pain in persons with obesity, although data from randomized, controlled trials are lacking

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However, baseline ASCVD or HF showed a statistically significant impact on MACE ( P = 0.0195, I 2 = 0.00%, R 2 = 100%), indicating that these comorbidities fully accounted for the variability in MACE events, while metformin use had a modest effect