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History of gallbladder disease : Patients with a history of gallstones or other gallbladder problems may have increased risk of complications

Rose MR, Flatt T, Graves JL, et al

10.1007/s11240-014-0458-8 146 ShibuM

Tirzepatide's common side effects are nausea, vomiting and diarrhea, typically mild to moderate and dose-dependent, with a personal history of medullary thyroid cancer or MEN2 syndrome as contraindications