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TAC surgery was associated with the upregulation of the hypertrophic cardiomyocyte biomarkers atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and -myosin heavy chain (-MHC), whereas these levels were significantly decreased in cardiac tissue samples from PQQ-treated mice that underwent TAC surgery (Figure 1J)
Preclinical animal research has explored BPC-157 in connection with gut barrier function, mucosal comfort, and a healthy inflammatory response within normal ranges in the GI tract
3 , 83ra4183ra41 (2011)
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