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Patients with anemia (e.g., sideroblastic anemia, thalassemia) may experience decreased iron absorption during high dose ascorbic acid therapy
This means the drug mimics the bodys hormone that stimulates production of the pigment melanin
Advantages : neurological action, crosses the blood-brain barrier, cognitive support, studied for age-related cognitive disorders, neuronal antioxidant action
If no potential covariable was included, it meant that none of the current potential covariables would affect efficacy
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