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Chen H, et al

Berthoud H-R, Zheng H

ZETA, Zactima Efficacy in Thyroid Cancer Assessment

The most frequent adverse effects are gastrointestinal and dose-related: Nausea, vomiting, diarrhoea, constipation, and abdominal discomfort - Typically worst during dose escalation and often resolve or attenuate with continued treatment and slower titration