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(Source: Side Effects and Patient Safety Concerns GLP-1 analogues frequently cause gastrointestinal distress, nausea, and vomiting as side effects, which may deter long-term use

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Yes, it can be

News-Medical+3EurekAlert!+3ASMBS+3 To put numbers on it: Surgical patients lost ~58 lbs in two years ( 24% of total body weight, or TBW) GLP-1 patients lost only ~12 lbs ( 4.7% TBW) over the same period EurekAlert!+2News-Medical+2 Even among GLP-1 users who continued therapy for a full year, weight loss averaged only ~7% TBWstill far less than surgical outcomes EurekAlert!+2ASMBS+2 Another rigorous analysis published in JAMA Surgery compared weight loss surgery and GLP-1 receptor agonists over two years

Coverage Varies Widely by Plan Some employer-sponsored plans offer generous coverage for weight-loss medications