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Description

Patients take the smallest dose daily for 30 days, then go up to the middle dose

10.1038/nm.2261 26 ColhounH

5-Amino-1MQ (5-amino-1-methylquinolinium) is the most studied inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme that acts as a metabolic brake in fat cells by depleting both SAM (S-adenosylmethionine) and NAD+ precursors