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Weight loss improves knee OA, with studies showing a 2% improvement in the WOMAC pain, function, and stiffness scores for every 1% reduction in body weight

Weight Loss Outcomes: 1.25 mg dose (20 weeks): 9.7% weight loss 5 mg dose (28 weeks): 16.2% weight loss 20 mg dose (36 weeks): 22.0% weight loss In contrast, placebo-treated participants showed minor weight gains of 1.9%, 2.3%, and 2.0% over the same periods

In short, BPC stands for Body Protection Compound and it is 15 amino acids long

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Patients with known severe hypersensitivity to tirzepatide or its ingredients, especially those who have experienced allergic reactions like anaphylaxis or angioedema