pregnant while taking tirzepatide and Pregnancy: Safety, Timing, and Planning Tirzepatide and Pregnancy: Safety, Risks,

However, gastrointestinal side effects such as nausea and vomiting may lead to dehydration, potentially affecting urinary patterns

Despite advances in the understanding of its clinical features, effective treatments remain elusive, necessitating further exploration of the underlying mechanisms and novel therapeutic targets

By mimicking GLP-1, it enhances insulin secretion, reduces glucagon release, slows gastric emptying, and suppresses appetite, effectively lowering blood sugar and aiding in weight reduction

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Methods Animals All animal experiments were performed using male mice to ensure that sex difference influences were excluded, and all animals were housed in specific pathogen-free (SPF) facilities condition with 20-25 C temperature and 45-55% humidity on a regular 12-hour lightdark cycle, and approved by the Animal Welfare Ethics Committee at Renmin Hospital of Wuhan University (No