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Anhedonia: Anhedonia is the inability to feel pleasure or enjoyment in activities that an individual normally finds pleasurable

Bain: Lecture and advisory board fees: AstraZeneca, Boehringer Ingelheim, Eli Lilly, Merck Sharp & Dohme, Novo Nordisk, Roche, Sanofi-Aventis

Unlike mass-produced FDA-approved drugs with decades of stability data, compounded preparations are assigned conservative beyond-use dates (BUDs) that account for variability in compounding conditions and ingredient sources

Some researchers also use objective measures like heart rate variability, which can reflect mitochondrial and autonomic function

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