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11.1% of Participants Reported Using GLP-1s for More Than 18 Months 9.7% of users reported using GLP-1s for 1 month

Most people notice these changes within one to two weeks after their last dose

Overall, the risks of bias were relatively low for the whole included trials (See Figure 5 )

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Another concern might be chemical changes to semaglutide or liraglutide that are sitting in the heated environment of the body for months