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For instance, reduced expression of PER1 and CRY1 has been associated with higher tumor grade and poor prognosis 27

Conversely, taxa enriched in PD, such as members of the Enterobacteriaceae family, Akkermansia, and Desulfovibrio, are associated with heightened lipopolysaccharide burden, mucin degradation, and increased generation of reactive oxygen species, collectively amplifying innate immune activation and pro-inflammatory cascades

Why is our Gut Microbiome So Important

Dysregulated YAP1/TAZ and TGF- signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice