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The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: chemical mechanisms and the effects of fluorine substitution

W., Dhatariya, K., Dungan, K., Hofland, J., Kalra, S., Kaltsas, G., Kapoor, N., Koch, C., Kopp, P., Korbonits, M., Kovacs, C

This can lead to side effects such as extreme fatigue, hunger pangs, and lightheadedness

We see it as a deeper breakdown in communication between the immune system, nutrient absorption, and gut

As this study comprehensively evaluated how microbes and their derived metabolites alter gut physiology by direct CNS-mediated gut sympathetic modulation, separate research implicates the role of the aryl hydrocarbon receptor (AHR) as a critical node in regulating gut physiology and neurogenesis (Obata et al., 2020