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Verbal consent was obtained via phone and has been appropriately documented

AE incidence was assessed as a supportive secondary safety endpoint in each trial

The structures of some isocereulides differed from that of cereulide by substitution of L- O -Val by L- O -Leu (isocereulide A), L-Val by L-Ala (isocereulide D), D-Ala by D-Ser (isocereulide C) and D- O -Leu by D- O -Val (isocereulide B), thus indicating a relaxed substrate specificity of the A domains and an inefficient proof reading by CesT 18

Prescriptions must come from a primary care physician or licensed medical doctor practicing within the US only

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