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Comparing DPP-4 Inhibitors to Other Type 2 Diabetes Medicines DPP-4 inhibitors produce moderate HbA1c reductions and are weight-neutral, but are less potent than GLP-1 receptor agonists and SGLT-2 inhibitors, which also offer cardiovascular and renal protective benefits not seen with gliptins

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We call this the diabesity epidemic, where its diabetes and obesity because obesity is really fueling new cases of type 2 diabetes