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In a new study reported in The Lancet, Tirzepatide, a GLP-1R/GIPR agonist, reduced alcohol's rewarding properties, locomotor stimulation, conditioned place preference, and accumbal dopamine release

For BMI 40+, or BMI 35+ with diabetes/sleep apnea, surgery generally produces more durable results

When interpreting our results, it is important to highlight that GLP-1RAs were associated with a reduced incidence of anxiety disorders, autism, bulimia nervosa, PTSD, and schizophrenia