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As described in our response to comments in this section of this final rule, we would apply ASM payment multipliers to all Part B payments for covered professional services to ASM participants during an ASM payment year, meaning that a separate payment code would be unnecessary and create an unnecessary burden

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Regarding the mechanism of SetCys-mediated ligation under strong reducing conditions, we hypothesized that the early formation of intermediate 5 is due to the interception of the reduced SetCys unit 2 by the thioester component (Fig

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