Liraglutide ameliorated the phosphorylated expressions of ERK and JNK interfered with by STZ and decreased the hyperphosphorylation of NFs (216)
The large molecular entities of both albiglutide and dulaglutide delay their renal clearance (92, 93)
Unlike other medications that might target a singular health issue for a limited period of time, GLP-1 drugs can drive sustained, long-term changes in how people eat, shop and manage their health, given that the medication acts as an appetite suppressant, and helps maintain muscle mass while promoting weight loss
Monitoring and follow-up: Regular follow-up during the first 3-6 months of therapy allows for symptom assessment, dose optimization, and early identification of complications
"We think that some of these people may be changing behavior, nutrition, lifestyle, [and] also may be changing the hormones in their body by being on [GLP-1 medications], changing how their brain sort of operates or functions permanently," Narula said
