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[DOI] [PubMed] [Google Scholar] 64.Fineman M, Weyer C, Maggs DG, Strobel S, Kolterman OG

GABAB1 receptor knockdown in prefrontal cortex induces behavioral aberrations associated with autism spectrum disorder in mice

Several additional percentage points of weight loss translate to significantly greater improvements in metabolic health markers, joint pain, mobility, and quality of life measures

Stratified by the level of weight reduction To explore the relationship between significant weight loss during treatment and long-term weight loss maintenance, we performed subgroup analyses of whether significant weight loss was associated with weight regain

The evidence here is nuanced and worth exploring in detail