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In an unmatched population-based casecontrol approach, we estimated a sample size of 258 individuals with QUANTO software, version 1.2.4, assuming a log-additive inheritance model at 5% significance and 80% power and using the following parameters based on our previous study 20 : an environmental exposure to Hg of 2.5%, a population risk of reduced estimated glomerular filtration rate (eGFR

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Glutathione is one of the most powerful intracellular antioxidants, supporting skin, liver, immune, and cellular health for both men and women

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Muramatsu M, Sankaranand VS, Anant S, Sugai M, Kinoshita K, Davidson NO, et al

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