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The integrated PK-PD findings, including nonlinear exposure, target tissue accumulation, and disruption of L-carnitine homeostasis, collectively elucidate mildronates mechanism of action through energy substrate depletion, as well as its intrinsic efficacy-toxicity duality

In 2015, Deepika played the role of "Mastani" (an Indian princess who was known to be very pale, almost translucent), the original first choice for the role was Aishwarya Rai Bachchan, who has always been much lighter than Deepika

The Sirio Libanes Research Ethics Committee has confirmed that no ethical approval is required

Louis-Post Dispatch, rushed to the aid of Mike Flanary , a 64-year-old videographer who collapsed from a heart attack in the visiting dugout at Busch Stadium before Sundays game between the Cardinals and Cubs

Sun D, Tainsky MA, Haddad R