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Biological fluid samples are readily available, and effective small changes in gene and protein expression are amplified on metabolites, thus making mass spectrometry detection easier and more sensitive, and reflecting the real pathophysiological state of organisms more directly and accurately (Zhou et al

Finally, we outline future directions within an ethnopharmacological perspective, integrating traditional knowledge with pharmacological innovation to inform multi target, standardized, and potentially personalized interventions for defined ASD endophenotypes

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American College Health Association (Review Article)