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Yassine HN, Solomon V, Thakral A, Sheikh-Bahaei N, Chui HC, Braskie MN, Schneider LS, Talbot K (2022) Brain energy failure in dementia syndromes: Opportunities and challenges for glucagon-like peptide-1 receptor agonists

We recognize that not every patient pursuing GLP-1 therapy has the same goal

Results TMAO activates quiescent, but not conventionally cultured, valve interstitial cells First, we sought to test the hypothesis that TMAO triggers VIC activation using primary female porcine VICs grown in standard culture

Levels of glutathione synthetase (GSS) were determined using Human Glutathione Synthetase ELISA Kit (Abcam, Cambridge, UK), while levels of glutathione (GSH) were determined with the GSH+GSSG / GSH Assay Kit (Colorimetric) (Abcam, Cambridge, UK)

KPV is a tripeptide consisting of Lysine, Proline, and Valine