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Notably, G/D-CuP exerted anti-inflammatory and antioxidative properties, promoting angiogenesis, fibroblast proliferation, and migration to accelerate wound healing without the need for additional bioactive substances

Improved metabolic status enhances GnRH frequency and amplitude

Similarly, A 2A R antagonists or genetic deletion of A 2A R were shown to improve short-term memory, working memory, reversal learning, goal-directed behavior, and fear conditioning in animal models used for different neurological diseases [51-56]

AMPK activation: MOTS-c activates AMP-activated protein kinase, the enzyme that functions as the cellular energy sensor

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