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These reducing agents function in a manner similar to that of GSH, except that DTT, because it has two thiol groups, forms an intramolecular disulfide in its oxidized form

[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Sun Y, Liu Y, Dian Y, Zeng F, Deng G, Lei S

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The two hTrxR1 molecules formed a twofold dimer as previously observed (Fig