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J Clin Endocrinol Metab 37(5):826828 Elahi D, Andersen DK, Brown JC et al (1979) Pancreatic alpha-and beta-cell responses to GIP infusion in normal man

That's in addition to, as mentioned by Gambit, excess alcohol causing issues with the liver which is the primary bodily store of B12

Phase IIb Results and Regulatory Status A larger Phase IIb trial involving over 500 overweight and obese subjects was conducted to further evaluate efficacy and safety

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