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The Jiang research group successfully established a neonatal rat model of necrotizing enterocolitis (NEC) by simulating the intestinal microenvironment of preterm infants using a multi-factorial induction approach that combined hypoxia, hyperosmolar formula feeding, and lipopolysaccharide (LPS) stimulation

its purposeful expansion

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Together, they serve as an experimental model for investigating parallel signaling pathways, receptor activation, and peptide synergy within endocrine systems

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