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If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every three to four days for another two to three weeks

As a result, they will feel more confident and independent living at home

J Inherit Metab Dis 2005

Unlabeled propionate was also detected in the eye, which may be produced by gut bacteria and enter the eye via the systemic circulation, or generated by ocular cells metabolizing pyruvate (96)

In this study, participants receiving ALA showed a marked reduction in the Neuropathy Symptoms Score compared to those who did not receive treatment, the patients treated with ALA reported an average time of 18.4 days for symptom relief (Pieralice et al., 2019)