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Hydroxocobalamin and methylene blue are also used off-label for the treatment of vasoplegia, poor cardiac output, and distributive shock [11]
The time it takes for vitamin B12 (cobalamin) treatment to produce noticeable effects varies considerably depending on the severity of deficiency, the route of administration, and individual patient factors
No Direct Metabolic Boost for Fat Storage : While B12 is crucial for metabolism, it doesn't directly trigger fat storage in the way, say, excess calories from food do
Another proposed mechanism involves the binding of homocysteine to the collagenous matrix of bone, which may modify collagen properties and reduce bone strength (reviewed in 113)