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The FDA has specifically flagged this issue as a safety concern

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Specifications Presentation: 10 mg per vial Purity: 99 %, confirmed by HPLC and LC-MS Form: white lyophilised powder Solubility: readily soluble in water (HO) Manufacturing: GMP-compliant, ISO 9001:2008 Documentation: third-party certificate of analysis per lot Intended use: in-vitro and laboratory research only Quality & documentation Every lot of Melanotan II is produced in a GMP-compliant, ISO-certified facility and independently verified by a third-party laboratory

And when appetite is suppressed, protein often becomes the first nutrient people unintentionally undereat, which is exactly the opposite of what helps protect muscle during weight loss

14 Important Safety Information: Side effects are common but usually temporary as your body adjusts