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[4] Some preclinical and early clinical research has explored its potential in contexts involving cerebral ischemia, though much of this evidence is preliminary or derived from Eastern European clinical populations and should be interpreted cautiously
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Shamriz 2019 reported anaphylaxis following a first dose of lixisenatide in a patient who had previously tolerated exenatide and liraglutide, demonstrating drug-specific rather than universal class-level hypersensitivity [10]