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The mainstay of treatment is an aggressive surgical approach with negative margins (R0 resection) followed by adjuvant radiotherapy for tumors with high grade, large size, and positive margins and the addition of chemotherapy for those who can tolerate it [3]
Sex hormones are also involved in regulating GH release particularly during puberty and also later in life
FFAR2/3: free fatty acid receptor 2/3
While GLP-1 drugs can be highly effective for weight loss and diabetes management, they work best as part of comprehensive treatment plans that include dietary changes and physical activity
175 PetkovaA
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