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This decline directly reflects the loss of key SCFA-producing taxa, especially within the Firmicutes and Lachnospiraceae families ( Table 1 provides a comprehensive overview of clinical evidence demonstrating SCFA alterations across different stages of DKD, highlighting the consistent pattern of butyrate depletion in DKD patients and the therapeutic potential of interventions that restore SCFA levels

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Genome-wide identification and analysis of the GGCT gene family in wheat