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Familial studies further support the role of genetic predisposition, with first-degree relatives of UC patients showing a higher risk of developing the disease

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It is challenging to define cellular senescence in erythrocytes, since these cells are terminally differentiated and their aging is not accompanied by the senescence-associated secretory phenotype (SASP) like in the case of nucleated cells [495]

10.1507/endocrj.EJ20-0006 17

This community faces unique health challenges including weight gain from mood stabilizers or antipsychotics, insulin resistance, and conditions like binge eating or polycystic ovary syndrome (PCOS)