AG142005: β-D-GalNAc-Butyl-Carboxylic Acid Pack Size:100 mg Galα(1-3)Galβ(1-4)GlcNAc-β-O-(CH2)4-COOH

Galα(1-3)Galβ(1-4)GlcNAc-β-O-(CH2)4-COOH

which can be removed under acidic conditions to reveal the free amine for conjugation

connected through a β-alanine linker equipped with a biotin tag through a hydrophilic PEG3 spacer

/ Triantennary GalNAc-β-Alanine-PEG3-Biotin / Tris-GalNAc-β-Ala-PEG3-Biotin

/ β-D-Gal-Ethyl-Azide / β-Gal-Et-N3

AG142005: β-D-GalNAc-Butyl-Carboxylic Acid Pack Size:100 mg Galα(1-3)Galβ(1-4)GlcNAc-β-O-(CH2)4-COOHC13H23NO8 321. 32 A D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a short butyl spacer. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on proteins and peptides to form stable amide bonds. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the