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AG142010: α-GalNAc-Butyl-Carboxy Methyl Ester Pack Size:50 mg α-D-GalNAc-Ser-NH-Biotin

SKU: 78456648014

4.2
USD200.00 USD244.00

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Description

α-D-GalNAc-Ser-NH-Biotin

the innermost N-glycan residue with the α1-6 core fucose that modulates antibody effector function and is a focus of biopharmaceutical glycoengineering

mimicking the inner N-glycan substructure released by endo-β-mannosidase activity

STF (Neu5Acα2-3Galβ1-3GalNAcα) at Thr 541

This compound presents an A2 biantennary N-glycan capped with α2-6-linked sialic acid (disialo) on an Asn core

AG142010: α-GalNAc-Butyl-Carboxy Methyl Ester Pack Size:50 mg α-D-GalNAc-Ser-NH-BiotinC14H25NO8 335. 35 An D N acetylgalactosamine (GalNAc) ligand equipped with a methyl ester protected carboxylic acid through a short butyl spacer. The methyl ester serves as a stable, protected form of the carboxylic acid that can be hydrolyzed under mild basic conditions (e. g., LiOH, NaOH) to unmask the free acid for downstream activation to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and subsequent coupling to amine functionalized platforms or

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