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Both methods predicted several compounds that exhibited similarity to remdesivir, with GS-6620 predicted as the top compound by both models

Mean and standard deviation values were obtained directly from the database

As the essential eNOS cofactor tetrahydrobiopterin (BH 4 ) is susceptible for oxidation, a landmark study by David Harrison's group 62 was able to proof the concept that superoxide produced by the Nox may indeed trigger eNOS uncoupling in the experimental animal model of DOCA-salt hypertension

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